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Cryptolepis sanguinolenta (Cryptolepis)

Rated 4.95 out of 5 based on 20 customer ratings
(20 customer reviews)

PRODUCT DETAILS

Botanical Name:

Cryptolepis sanguinolenta

Common Name(s):

Cryptolepis
Ghanaian quinine

Part Used: Root
Percentage of Alcohol Used: 65%
Herb to Menstruum Ratio: 1:4
Production Method: Whole-herb Percolation Extraction

INGREDIENTS

  • Cryptolepis sanguinolenta (Cryptolepis)
  • Gluten-Free Pharmaceutical-Grade Alcohol
  • Distilled Water

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Vegan

GLUTEN FREE

ALL NATURAL

CRUELTY FREE

SUSTAINABLE

NON GMO

*This product is not intended to diagnose, treat, cure, or prevent any disease. Please consult your health care provider for further information & dosing recommendations.

*This product is not intended to diagnose, treat, cure, or prevent any disease.
Please consult your health care provider for further information & dosing recommendations.

Additional Information About Cryptolepis sanguinolenta (Cryptolepis)

Cryptolepis sanguinolenta, a climbing shrub native to Africa, Papua New Guinea, and Australia, is a key broad-spectrum systemic antibiotic herb. Predominantly found in hot climates, its vibrant yellow root is widely utilized for its medicinal prowess.

Growing Conditions
Thriving in a hot climate, Cryptolepis sanguinolenta is a climbing shrub with medicinal roots and leaves, primarily harvested in the wild. The herb's vibrant yellow root, rich in alkaloids, is its distinguishing feature.

Terminology
Cryptolepis sanguinolenta's relationship with Cryptolepis buchanani, native to India and used in Ayurvedic medicine, remains uncertain. Currently Cryptolepis sanguinolenta is considered the most medically potent variety.

Constituents
Key alkaloids, including cryptolepine, quindolin, neocryptolepine, cryptolepine hydrochloride, hydroxycryptolepin, and cryptoheptine, render Cryptolepis sanguinolenta a potent herb.

When taking a Cryptolepis tincture, extraction with 60% ethanol is crucial for preserving its alkaloid-rich medicinal compounds. Tinctures made with a higher or lower ethanol concentration may retain the yellow appearance, but will not contain the medically active alkaloids.

Scientific Studies
Scientific evidence supports Cryptolepis sanguinolenta's antibacterial efficacy, particularly against gram-positive bacteria, with conflicting evidence regarding its impact on Candida spp. Notably, the herb exhibits promise against multi-drug resistant malaria in vitro.

Human Studies
Human studies indicate transient elevations in liver enzymes and uric acid levels with Cryptolepis sanguinolenta use, which normalized upon discontinuation. Historical data suggests long-term use is safe, though caution is advised when combined with central nervous system depressants, hypnotics, and sedatives.

Cautions and Side Effects
No known cryptolepis sanguinolenta side effects side effects have been reported in human trials, mice, or rabbits. Caution is still advised when combining with central nervous system depressants and sedative medications, underlining the herb's safety in historical and modern contexts.

Cryptolepis sanguinolenta
Cryptolepis sanguinolenta

References

1. Natural Treatments For Lyme Coinfections - Anaplasma, Babesia, and Ehrlichia. By Stephen Harrod Buhner
2. Herbal Antibiotics. Natural alternatives for treating drug-resistant bacteria. By Stephen Harrod Buhner.
3. Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi. Jie Feng et al. Front Med (Lausanne). 2020 Feb 21:7:6. doi: 10.3389/fmed.2020.00006. eCollection 2020. https://pubmed.ncbi.nlm.nih.gov/32154254/
4. Cryptolepis sanguinolenta activity against diarrhoeal bacteria. A Paulo et al. J Ethnopharmacol. 1994 Oct;44(2):73-7. doi: 10.1016/0378-8741(94)90071-x. https://pubmed.ncbi.nlm.nih.gov/7853867/
5. Botanical Medicines Cryptolepis sanguinolenta, Artemisia annua, Scutellaria baicalensis, Polygonum cuspidatum, and Alchornea cordifolia Demonstrate Inhibitory Activity Against Babesia duncani. Yumin Zhang et al. Front Cell Infect Microbiol. 2021 Mar 8:11:624745. doi: 10.3389/fcimb.2021.624745. eCollection 2021. https://pubmed.ncbi.nlm.nih.gov/33763384/
6. Antimicrobial, antioxidant activities, and total phenolic contents of Pycnanthus angolensis Sap and Cryptolepis sanguinolenta root extracts. Francis Adu-Amankwaah et al. BMC Complement Med Ther. 2023 Jun 21;23(1):205. doi: 10.1186/s12906-023-04006-8. https://pubmed.ncbi.nlm.nih.gov/37344802/
7. The clinical efficacy of cryptolepis sanguinolenta in the treatment of malaria. Michael S Tempesta. Ghana Med J. 2010 Mar;44(1):1-2. https://pubmed.ncbi.nlm.nih.gov/21326982/
8. Antiplasmodial activity of Cryptolepis sanguinolenta alkaloids from leaves and roots. A Paulo et al. Planta Med. 2000 Feb;66(1):30-4. doi: 10.1055/s-2000-11106. https://pubmed.ncbi.nlm.nih.gov/10705730/

Customer reviews
Rated 4.95 out of 5
4.95 out of 5 stars
  • 5 star:
    95%
  • 4 star:
    5%
  • 3 star:
    0%
  • 2 star:
    0%
  • 1 star:
    0%

20 reviews for Cryptolepis sanguinolenta (Cryptolepis)

  1. G
    Genevieve C Verified Buyer 03/26/2022
    Rated 5 out of 5

    seems to do great for my symptoms

    Was this review helpful? 0 0
  2. J
    Jessica Verified Buyer 01/27/2022
    Rated 5 out of 5

    Super fast shipping, and Alex was very helpful and knowledgeable about the tinctures. We will definitely order again!

    Was this review helpful? 0 0
  3. G
    George Verified Buyer 01/15/2022
    Rated 5 out of 5

    This tincture works! I’m starting to feel better after years of trying so many different therapies.

    Was this review helpful? 0 0
  4. M
    Merle Verified Buyer 04/01/2022
    Rated 5 out of 5

    This was all good, exactly what I wanted, arrived pretty quick, and in perfect condition. It’s too early to tell whether or not it worked. I didn’t realize the dosage meant that I finished it a little sooner than I thought it would, but whatever, there’s a learning curve for DYI medicine. I’m also glad to support a local business.

    Was this review helpful? 0 0
  5. M
    Merle Verified Buyer 04/01/2022
    Rated 5 out of 5

    This was all good, exactly what I wanted, arrived pretty quick, and in perfect condition. It’s too early to tell whether or not it worked. I didn’t realize the dosage meant that I finished it a little sooner than I thought it would, but whatever, there’s a learning curve for DYI medicine. I’m also glad to support a local business. Those hippies out there in Nelson are living the dream!

    Was this review helpful? 0 0
  6. K
    Kathleen Verified Buyer 03/01/2022
    Rated 5 out of 5

    very happy

    Was this review helpful? 0 0
  7. R
    Robert Verified Buyer 11/28/2022
    Rated 5 out of 5

    Great product. I will buy more from them.

    Was this review helpful? 0 0
  8. V
    Victoria Verified Buyer 09/20/2022
    Rated 5 out of 5

    very impressed by the quality

    Was this review helpful? 0 0
  9. D
    Dylan Verified Buyer 12/23/2021
    Rated 5 out of 5

    Apex Botanicals has exceeded my expectations. the product, the support and the fast shipping. I’ll order again

    Was this review helpful? 0 0
  10. M
    Minkeygirl Verified Buyer 12/05/2021
    Rated 5 out of 5

    Have not started this, using up my old one but have heard great things about apex. So I’m sure this will be good.

    Was this review helpful? 0 0
  11. P
    Penelope Verified Buyer 05/08/2021
    Rated 5 out of 5

    So far this tincture is pretty good. it doesn’t cause any negative side effects. taste isn’t the greatest, but thats to be expected. I’ll definitely continue to use it.

    Was this review helpful? 0 0
  12. S
    Scarlett Verified Buyer 10/31/2022
    Rated 4 out of 5

    Thank you!

    Was this review helpful? 0 0
  13. M
    Maria Verified Buyer 01/19/2022
    Rated 5 out of 5

    Truly a game-changer.

    Was this review helpful? 0 0
  14. V
    Veracity Verified Buyer 06/27/2023
    Rated 5 out of 5

    Great quality. Exactly like description. Met my expectations!

    Was this review helpful? 0 0
  15. M
    Michael Verified Buyer 01/20/2023
    Rated 5 out of 5
    Was this review helpful? 0 0
  16. M
    Macland Verified Buyer 08/09/2023
    Rated 5 out of 5
    Was this review helpful? 0 0
  17. K
    Kathleen Verified Buyer 10/22/2023
    Rated 5 out of 5

    The tincture was received in perfect condition. It’s my second bottle and I’ve been more than pleased by its benefits for me!

    Was this review helpful? 0 0
  18. D
    David Verified Buyer 10/14/2023
    Rated 5 out of 5

    Item is just what I was looking for! Perfect product

    Was this review helpful? 0 0
  19. L
    Layla Verified Buyer 03/03/2021
    Rated 5 out of 5

    I’ve tried so many different supplements and remedies for my Lyme symptoms, so far cryptolepis is the only thing that’s helped. hope it keeps working

    Was this review helpful? 0 0
  20. S
    Samuel Verified Buyer 06/22/2022
    Rated 5 out of 5

    I tried a lot of different supplements and tinctures and Apex is definitely a standout. Customer service is better than most. It’s too soon to tell if they’re really effective but I’m impressed with the quality of the products so far. I recommend

    Was this review helpful? 0 0
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Free Lyme Protocol Guide - Apex Botanicals

SHARING THE GIFT OF WELLNESS

FREE Herbal Protocol Guide for Lyme &
Co-Infections

This guide, written by our Lyme-literate experts, is designed to offer clarity amidst the confusion of endless treatment choices.

You'll gain insights into the nuanced physiological effects of the Lyme bacteria on various body systems and how herbs and supplements play a pivotal role in addressing these challenges.

By the end you'll have created your very own customized treatment protocol, tailored to your unique needs!

FAQ

What makes Apex Botanical tinctures different from other herbal tinctures?

Our tinctures stand out due to the premium quality of herbs we use. Crafted at a concentration of 1:4, our herbal tinctures prioritize both potency and effectiveness.

Unlike many other companies that employ a uniform alcohol percentage across all products, our approach is nuanced. We tailor the alcohol concentration for each herb based on the distinct medicinal properties of the plant.

This strategy reflects our commitment to a sophisticated extraction of medicinal compounds, effectively setting Apex Botanicals apart in the realm of herbal tinctures.

How should I consume my herbal tincture?

Herbal tinctures are generally taken on an empty stomach (1 hour before and after meals). They can be taken directly or added to 1oz of water if the taste is hard to swallow.

Dosing of herbal tinctures will generally vary from 1 drop once per day up to 1 tsp 3 times per day. When taking anti-microbial herbal tinctures, starting at a lower dose and increasing slowly is the general rule of thumb.

*Be sure to speak with your primary care provider to determine the correct dose for your needs.

How long should I take my herbal tincture for?

The length of time a tincture should be taken will vary considerably based on your state of health, the infection / symptom you’re trying to treat and other medications or treatments you are concurrently taking.

Most people with chronic tick-borne infections take an herbal tincture for between 3 months and 2 years.

As a general rule, its recommended to take an herbal tincture for at least 1 month to see the best results.

Are herbal tinctures safe for children?

Generally speaking, it is safe for children to consume herbal tinctures, but dosing should be adjusted. Refrence 'Clarks Rule' for further information.

*Always consult your primary care provider before starting a new protocol or giving your child herbal tinctures.

Are herbal tinctures safe during pregnancy or while breastfeeding?

Some herbs are strictly contraindicated in pregnancy and should be avoided. We do our best to indicate this on the product information page but are not held liable for any errors or omissions.

If you are pregnant or breastfeeding consult your primary care provider before consuming any herbal tinctures.

Will my herbal tincture interact with medications or supplements?

Interactions of herbal tinctures with medications or supplements do exist. We strongly recommended consulting with your primary care provider or pharmacist before taking any herbal tinctures if you are concerned about potential contraindications.

What does a 1:4 ratio imply and how does it compare to 1:2 or 1:5+?

The ratio describes the concentration of a tincture. We use a 1:4 ratio, meaning 1 part dried herb (in grams) to 4 parts menstruum (the combined alcohol and herb).

A ratio of 1:5 has more liquid to the same amount of herb and is therefore more diluted.

A ratio of 1:10 or higher is very diluted and requires very high daily doses and is not recommended.

Tinctures made at 1:2 are often too concentrated for Lyme patients and commonly induce Herx reactions that can be very intense.

Most tinctures on the market are made at 1:5. We’ve chosen to use 1:4 to ensure greater potency while still being very safe and tolerable.

Does higher alcohol content mean an herbal tincture is more or less potent?

Using the correct alcohol percentage to extract the specific medicinal constituents of that herb is of highest importance when making a tincture. Using more or less alcohol essentially reflects the chemical nature of the compounds that we want to extract into the liquid portion.

A tincture made at 40% versus one made at 80% is not twice at strong. It simply implies that for the first herb, 40% alcohol will optimally extract the medicinal qualities. For the second herb, 80% is the concentration for optimal extraction.

We’ve gone to great lengths to ensure that our tinctures are made using the correct concentrations.

*Please note that not all herbal tinctures on the market are made with the appropriate alcohol concentration so use our site as a reference or conduct your own research to make sure you’re purchasing the best formulated tincture possible.

Click here to read our complete list of Frequently Asked Questions.